“What I realized while working on ‘4Chambers’ is that everything in your heart, everything you feel — it’s all the brain,” she said.

In an early version of the new work, Ms. Oberfelder gave herself the comedic role of a fact-dispensing “brain guru.” But she wasn’t satisfied.

“The poetry of the movement was getting lost in the didacticness of the science,” she said. “So I thought, why not get the audience to try to feel their brains, without telling them how? To set up situations where they’re interacting not only with their minds intellectually but passing that down through the body, being in a physical space with other bodies, making connections with others and with sensation?”

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